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Annals of the New York Academy of Sciences
Signal Transduction Pathways, Chromatin Structures, and Gene Expression Mechanisms as Therapeutic Targets
Volume 1030 published December 2004

Editors:
Marc Diederich


[Index by Author]

Contents:

       Part I. Cell Signaling Pathways in Health and Disease
       Part II. MAP Kinase Pathways as Therapeutic Targets
       Part III. Signal Transduction Pathways in Neurodegenerative Diseases
       Part IV. Apoptotic Signaling Pathways
       Part V. Chemopreventive Agents Interfering with Cell Signaling Pathways
       Part VI. Gene Expression Mechanisms as Therapeutic Targets
       Part VII. Transcriptional Control Mechanisms as Therapeutic Targets
       Part VIII. Chromatin Structure as a Therapeutic Target

 
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MARC DIEDERICH
Preface
Ann NY Acad Sci 2004 1030: xiii. [Full Text]  

Part I. Cell Signaling Pathways in Health and Disease:

SYLVIE DELHALLE, ROMAIN BLASIUS, MARIO DICATO, and MARC DIEDERICH
A Beginner's Guide to NF-{kappa}B Signaling Pathways
Ann NY Acad Sci 2004 1030: 1-13. [Abstract] [Full Text]  

DOMINIQUE THURINGER
The Vascular Endothelial Growth Factor-Induced Disruption of Gap Junctions Is Relayed by an Autocrine Communication via ATP Release in Coronary Capillary Endothelium
Ann NY Acad Sci 2004 1030: 14-27. [Abstract] [Full Text]  

GWÉNOLA BOULDAY, JULIETTE FITAU, STÉPHANIE COUPEL, JEAN-PAUL SOULILLOU, and BÉATRICE CHARREAU
Exogenous Tissue Inhibitor of Metalloproteinase-1 Promotes Endothelial Cell Survival Through Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway
Ann NY Acad Sci 2004 1030: 28-36. [Abstract] [Full Text]  

JÜRGEN BRIEGER, PETRA SCHROEDER, JAN GOSEPATH, and WOLF J. MANN
The Cyclooxygenase Inhibitor Flurbiprofen Reduces Radiation-Induced Angiogenic Growth Factor Secretion of Squamous Cell Carcinoma Cell Lines
Ann NY Acad Sci 2004 1030: 37-42. [Abstract] [Full Text]  

YANG-SOOK CHUN, EUN-JIN YEO, HWA-JIN SUH, and JONG-WAN PARK
Spontaneous Generation of Reactive Oxygen Species in the Mixture of Cyanide and Glycerol
Ann NY Acad Sci 2004 1030: 43-51. [Abstract] [Full Text]  

SONIA COLOMBO, FRANCESCO PERI, RENATA TISI, FRANCESCO NICOTRA, and ENZO MARTEGANI
Design and Characterization of a New Class of Inhibitors of Ras Activation
Ann NY Acad Sci 2004 1030: 52-61. [Abstract] [Full Text]  

S DOMINICI, L PIERI, A PAOLICCHI, V DE TATA, F ZUNINO, and A POMPELLA
Endogenous Oxidative Stress Induces Distinct Redox Forms of Tumor Necrosis Factor Receptor-1 in Melanoma Cells
Ann NY Acad Sci 2004 1030: 62-68. [Abstract] [Full Text]  

C ENSINGER, G SPIZZO, P MOSER, I TSCHOERNER, R PROMMEGGER, M GABRIEL, G MIKUZ, and K W SCHMID
Epidermal Growth Factor Receptor as a Novel Therapeutic Target in Anaplastic Thyroid Carcinomas
Ann NY Acad Sci 2004 1030: 69-77. [Abstract] [Full Text]  

NICOLAS ETIQUE, DOMINIQUE CHARDARD, AMAND CHESNEL, STEPHANE FLAMENT, and ISABELLE GRILLIER-VUISSOZ
Analysis of the Effects of Different Alcohols on MCF-7 Human Breast Cancer Cells
Ann NY Acad Sci 2004 1030: 78-85. [Abstract] [Full Text]  

JEUNG HEE AN, JIYOUNG KIM, and JINSIL SEONG
Redox Signaling by Ionizing Radiation in Mouse Liver
Ann NY Acad Sci 2004 1030: 86-94. [Abstract] [Full Text]  

JIYOUNG KIM, JINSIL SEONG, and SUNG HEE KIM
Enhancement of Tumor Response by Farnesyltransferase Inhibitor in C3H/HeJ Hepatocarcinoma
Ann NY Acad Sci 2004 1030: 95-102. [Abstract] [Full Text]  

SPIRO M. KONSTANTINOV, MINA M. MINDOVA, PANAYOT T. GOSPODINOV, and PENKA I. GENOVA
Three-Dimensional Bioreactor Cultures: A Useful Dynamic Model for the Study of Cellular Interactions
Ann NY Acad Sci 2004 1030: 103-115. [Abstract] [Full Text]  

YASUHIRO KUMEI, SADAO MORITA, HIROSHI NAKAMURA, HIDEO AKIYAMA, HISAKO KATANO, HITOYATA SHIMOKAWA, and KEI'ICHI OHYA
Platelet-Activating Factor Receptor Signals in Rat Osteoblasts during Spaceflight
Ann NY Acad Sci 2004 1030: 116-120. [Abstract] [Full Text]  

YASUHIRO KUMEI, SADAO MORITA, HIROSHI NAKAMURA, HISAKO KATANO, KEI'ICHI OHYA, HITOYATA SHIMOKAWA, CLARENCE F. SAMS, and PEGGY A. WHITSON
Osteoblast Responsiveness to 1{alpha},25-Dihydroxyvitamin D3 during Spaceflight
Ann NY Acad Sci 2004 1030: 121-124. [Abstract] [Full Text]  

ANIS LARBI, GILLES DUPUIS, NADINE DOUZIECH, ABDELOUAHED KHALIL, and TAMÀS FÜLÖP, JR
Low-Grade Inflammation with Aging Has Consequences for T-Lymphocyte Signaling
Ann NY Acad Sci 2004 1030: 125-133. [Abstract] [Full Text]  

SONJA LEVANAT, VESNA MUSANI, ARIJANA KOMAR, and S ORESKOVIC
Role of the Hedgehog/Patched Signaling Pathway in Oncogenesis: A New Polymorphism in the PTCH Gene in Ovarian Fibroma
Ann NY Acad Sci 2004 1030: 134-143. [Abstract] [Full Text]  

PAUL D. MARONI, SWEATY KOUL, RANDALL B. MEACHAM, PARAMJIT S. CHANDHOKE, and HARI K. KOUL
Effects of Oxalate on IMCD Cells: A Line of Mouse Inner Medullary Collecting Duct Cells
Ann NY Acad Sci 2004 1030: 144-149. [Abstract] [Full Text]  

YOSHIHIKO MIYATA and EISUKE NISHID
Supervision of Multiple Signaling Protein Kinases by the CK2-Cdc37 Couple, a Possible Novel Cancer Therapeutic Target
Ann NY Acad Sci 2004 1030: 150-157. [Abstract] [Full Text]  

SADAO MORITA, HIROSHI NAKAMURA, YASUHIRO KUMEI, HITOYATA SHIMOKAWA, KEIICHI OHYA, and KENICHI SHINOMIYA
Hypergravity Stimulates Osteoblast Phenotype Expression: A Therapeutic Hint for Disuse Bone Atrophy
Ann NY Acad Sci 2004 1030: 158-161. [Abstract] [Full Text]  

CAROLA PORCILE, ADRIANA BAJETTO, SIMONE BARBERO, PAOLO PIRANI, and GENNARO SCHETTINI
CXCR4 Activation Induces Epidermal Growth Factor Receptor Transactivation in an Ovarian Cancer Cell Line
Ann NY Acad Sci 2004 1030: 162-169. [Abstract] [Full Text]  

JOSIANE SANCÉAU and JUANA WIETZERBIN
Downregulation of Angiogenic Factors in Ewing Tumor Xenografts by the Combination of Human Interferon-{alpha} or Interferon-ß with Ifosfamide
Ann NY Acad Sci 2004 1030: 170-178. [Abstract] [Full Text]  

JINSIL SEONG, HEE CHUL PARK, JIYOUNG KIM, UN JUNG KIM, and BAE WHAN LEE
Radiation-Induced Alteration of Pain-Related Signals in an Animal Model with Bone Invasion from Cancer
Ann NY Acad Sci 2004 1030: 179-186. [Abstract] [Full Text]  

MARCO SGARBANTI, GIULIA MARSILI, ANNA LISA REMOLI, BARBARA RIDOLFI, EMILIA STELLACCI, ALESSANDRA BORSETTI, BARBARA ENSOLI, and ANGELA BATTISTINI
Analysis of the Signal Transduction Pathway Leading to Human Immunodeficiency Virus-1-Induced Interferon Regulatory Factor-1 Upregulation
Ann NY Acad Sci 2004 1030: 187-195. [Abstract] [Full Text]  

WEI LI, LI-HUA XU, and XI-MING YUAN
Macrophage Hemoglobin Scavenger Receptor and Ferritin Accumulation in Human Atherosclerotic Lesions
Ann NY Acad Sci 2004 1030: 196-201. [Abstract] [Full Text]  

WEI LI, ANNA HELLSTEN, JEROME DINGA NYHALAH, and XI-MING YUAN
Enhanced Expression of Natural Resistance-Associated Macrophage Protein 1 in Atherosclerotic Lesions May Be Associated with Oxidized Lipid-Induced Apoptosis
Ann NY Acad Sci 2004 1030: 202-207. [Abstract] [Full Text]  

Part II. MAP Kinase Pathways as Therapeutic Targets:

EMMANUEL VIALA and JACQUES POUYSSÉGUR
Regulation of Tumor Cell Motility by ERK Mitogen-Activated Protein Kinases
Ann NY Acad Sci 2004 1030: 208-218. [Abstract] [Full Text]  

CATHERINE ALEXIA, MALIKA LASFER, and ANDRÉ GROYER
Role of Constitutively Activated and Insulin-Like Growth Factor-Stimulated ERK1/2 Signaling in Human Hepatoma Cell Proliferation and Apoptosis: Evidence for Heterogeneity of Tumor Cell Lines
Ann NY Acad Sci 2004 1030: 219-229. [Abstract] [Full Text]  

SAFIA COSTES, CHRISTINE LONGUET, CHRISTOPHE BROCA, OMAR FARUQUE, EL HABIB HANI, DOMINIQUE BATAILLE, and STEPHANE DALLE
Cooperative Effects between Protein Kinase A and p44/p42 Mitogen-Activated Protein Kinase to Promote cAMP-Responsive Element Binding Protein Activation after ß Cell Stimulation by Glucose and Its Alteration Due to Glucotoxicity
Ann NY Acad Sci 2004 1030: 230-242. [Abstract] [Full Text]  

HARI K. KOUL, PAUL D. MARONI, RANDALL B. MEACHAM, DAVID CRAWFORD, and SWEATY KOUL
p42/p44 Mitogen-Activated Protein Kinase Signal Transduction Pathway: A Novel Target for the Treatment of Hormone-Resistant Prostate Cancer?
Ann NY Acad Sci 2004 1030: 243-252. [Abstract] [Full Text]  

SWEATY KOUL, MEI HUANG, LAKSHMI CHATURVEDI, RANDALL B. MEACHAM, and HARI K. KOUL
p42/p44 Mitogen-Activated Protein Kinase Signal Transduction Pathway Regulates Interleukin-6 Expression in PC3 Cells, a Line of Hormone-Refractory Prostate Cancer Cells
Ann NY Acad Sci 2004 1030: 253-257. [Abstract] [Full Text]  

KI WON LEE, JI WON JUNG, KYUNG-SUN KANG, and HYONG JOO LEE
p38 Is a Key Signaling Molecule for H-ras-Induced Inhibition of Gap Junction Intercellular Communication in Rat Liver Epithelial Cells
Ann NY Acad Sci 2004 1030: 258-263. [Abstract] [Full Text]  

ALESSANDRO MASSA, FEDERICA BARBIERI, CINZIA AIELLO, RODOLFO IULIANO, SARA ARENA, ALESSANDRA PATTAROZZI, ALESSANDRO CORSARO, VALENTINA VILLA, ALFREDO FUSCO, GIANLUIGI ZONA, RENATO SPAZIANTE, GENNARO SCHETTINI, and TULLIO FLORIO
The Phosphotyrosine Phosphatase {eta} Mediates Somatostatin Inhibition of Glioma Proliferation via the Dephosphorylation of ERK1/2
Ann NY Acad Sci 2004 1030: 264-274. [Abstract] [Full Text]  

MASAHIKO SHIBAZAKI, TAKAHASHI TAKEUCHI, SOHEL AHMED, and HIDEAKI KIKUCHIA
Blockade by SB203580 of Cyp1a1 Induction by 2,3,7,8-Tetrachlorodibenzo-p-dioxin, and the Possible Mechanism: Possible Involvement of the p38 Mitogen-Activated Protein Kinase Pathway in Shuttling of Ah Receptor Overexpressed in COS-7 Cells
Ann NY Acad Sci 2004 1030: 275-281. [Abstract] [Full Text]  

Part III. Signal Transduction Pathways in Neurodegenerative Diseases:

DEBOMOY K. LAHIRI
Functional Characterization of Amyloid ß Precursor Protein Regulatory Elements: Rationale for the Identification of Genetic Polymorphism
Ann NY Acad Sci 2004 1030: 282-288. [Abstract] [Full Text]  

CARLO BERTONI-FREDDARI, PATRIZIA FATTORETTI, and MANUELA MALATESTA
Increased Intracellular Ionic Content Is Correlated with a Decreased Perichromatin Granule Density in Old Neurons
Ann NY Acad Sci 2004 1030: 289-296. [Abstract] [Full Text]  

B BILLINGS, S A. SMITH, Z ZHANG, D K. LAHIRI, and G J. KOTWAL
Lack of N1L Gene Expression Results in a Significant Decrease of Vaccinia Virus Replication in Mouse Brain
Ann NY Acad Sci 2004 1030: 297-302. [Abstract] [Full Text]  

PATRIZIA FATTORETTI, CARLO BERTONI-FREDDARI, BELINDA GIORGETTI, and MARTA BALIETTI
Increased Mitochondrial and Nuclear Gene Expression of Cytochrome Oxidase Subunits I and IV in Neuronal Aging
Ann NY Acad Sci 2004 1030: 303-309. [Abstract] [Full Text]  

DEBOMOY K. LAHIRI and YUAN-WEN GE
Role of the APP Promoter in Alzheimer's Disease: Cell Type-Specific Expression of the ß-Amyloid Precursor Protein
Ann NY Acad Sci 2004 1030: 310-316. [Abstract] [Full Text]  

MEI-HUA LI, JUNG-HEE JANG, BUXIANG SUN, and YOUNG-JOON SURH
Protective Effects of Oligomers of Grape Seed Polyphenols Against ß-Amyloid-Induced Oxidative Cell Death
Ann NY Acad Sci 2004 1030: 317-329. [Abstract] [Full Text]  

EMANUELA REPETTO, CLAUDIO RUSSO, VALENTINA VENEZIA, MARIO NIZZARI, ROGER M. NITSCH, and GENNARO SCHETTINI
BACE1 Overexpression Regulates Amyloid Precursor Protein Cleavage and Interaction with the ShcA Adapter
Ann NY Acad Sci 2004 1030: 330-338. [Abstract] [Full Text]  

VALENTINA VENEZIA, CLAUDIO RUSSO, EMANUELA REPETTO, MARIO NIZZARI, ELISABETTA VIOLANI, PIA CARLO, BIANCA MARCHETTI, and GENNARO SCHETTINI
Apoptotic Cell Death and Amyloid Precursor Protein Signaling in Neuroblastoma SH-SY5Y Cells
Ann NY Acad Sci 2004 1030: 339-347. [Abstract] [Full Text]  

Part IV. Apoptotic Signaling Pathways:

M BRAGADIN, G SCUTARI, A FOLDA, A BINDOLI, and M P RIGOBELLO
Effect of Metal Complexes on Thioredoxin Reductase and the Regulation of Mitochondrial Permeability Conditions
Ann NY Acad Sci 2004 1030: 348-354. [Abstract] [Full Text]  

CHRISTIAN BRONNER, MARIE-ALINE TROTZIER, ODILE FILHOL, CLAUDE COCHET, CÉCILE ROCHETTE-EGLY, MARIE SCHÖLLER-GUINARD, JEAN-PAUL KLEIN, and MARC MOUSLI
The Antiapoptotic Protein ICBP90 Is a Target for Protein Kinase 2
Ann NY Acad Sci 2004 1030: 355-360. [Abstract] [Full Text]  

LAWRENCE C.-M. CHIU, ELAINE Y.-L. WONG, and VINCENT E.C. OOI
Docosahexaenoic Acid from a Cultured Microalga Inhibits Cell Growth and Induces Apoptosis by Upregulating Bax/Bcl-2 Ratio in Human Breast Carcinoma MCF-7 Cells
Ann NY Acad Sci 2004 1030: 361-368. [Abstract] [Full Text]  

EZZATOLLAH KEYHANI and JACQUELINE KEYHANI
Plasma Membrane Alteration Is an Early Signaling Event in Doxorubicin-Induced Apoptosis in the Yeast Candida utilis
Ann NY Acad Sci 2004 1030: 369-376. [Abstract] [Full Text]  

MARIUSZ KODA, JOANNA RESZEC, MARIOLA SULKOWSKA, LUIZA KANCZUGA-KODA, and STANISLAW SULKOWSKI
Expression of the Insulin-Like Growth Factor-I Receptor and Proapoptotic Bax and Bak Proteins in Human Colorectal Cancer
Ann NY Acad Sci 2004 1030: 377-383. [Abstract] [Full Text]  

LELA B. KORICANAC, DANIJELA V. TODOROVIC, NATASA M. POPOVIC, MIROSLAV A. DEMAJO, SABERA D. RUZDIJIC, and ALEKSANDRA M. RISTI-FIRA
Inhibition of B16 Mouse Melanoma Cell Growth and Induction of Apoptotic Cell Death with 8-Chloroadenosine-3',5'-monophosphate and Tiazofurin
Ann NY Acad Sci 2004 1030: 384-392. [Abstract] [Full Text]  

RUTA NAVAKAUSKIENE, GRAZINA TREIGYTE, JURATE SAVICKIENE, ARUNAS GINEITIS, and KARL-ERIC MAGNUSSON
Alterations in Protein Expression in HL-60 Cells during Etoposide-Induced Apoptosis Modulated by the Caspase Inhibitor ZVAD.fmk
Ann NY Acad Sci 2004 1030: 393-402. [Abstract] [Full Text]  

UWE PAASCH, SONJA GRUNEWALD, SYLVIA DATHE, and HANS-JUERGEN GLANDER
Mitochondria of Human Spermatozoa Are Preferentially Susceptible to Apoptosis
Ann NY Acad Sci 2004 1030: 403-409. [Abstract] [Full Text]  

OCK JIN PARK and JANG-IN SHIN
Proapoptotic Potentials of Genistein Under Growth Stimulation by Estrogen
Ann NY Acad Sci 2004 1030: 410-418. [Abstract] [Full Text]  

JOANNA RESZEC, MARIOLA SULKOWSKA, MARIUSZ KODA, LUIZA KANCZUGA-KODA, and STANISLAW SULKOWSKI
Expression of Cell Proliferation and Apoptosis Markers in Papillomas and Cancers of Conjunctiva and Eyelid
Ann NY Acad Sci 2004 1030: 419-426. [Abstract] [Full Text]  

WEI LI and XI-MING YUAN
Increased Expression and Translocation of Lysosomal Cathepsins Contribute to Macrophage Apoptosis in Atherogenesis
Ann NY Acad Sci 2004 1030: 427-433. [Abstract] [Full Text]  

Part V. Chemopreventive Agents Interfering with Cell Signaling Pathways:

BHARAT B. AGGARWAL and SHISHIR SHISHODIA
Suppression of the Nuclear Factor-{kappa}B Activation Pathway by Spice-Derived Phytochemicals: Reasoning for Seasoning
Ann NY Acad Sci 2004 1030: 434-441. [Abstract] [Full Text]  

ROMAIN BLASIUS, ANNELYSE DUVOIX, FRANCK MORCEAU, MICHAËL SCHNEKENBURGER, SYLVIE DELHALLE, ESTELLE HENRY, MARIO DICATO, and MARC DIEDERICH
Curcumin Stability and Its Effect on Glutathione S-Transferase P1-1 mRNA Expression in K562 Cells
Ann NY Acad Sci 2004 1030: 442-448. [Abstract] [Full Text]  

EZZATOLLAH KEYHANI and JACQUELINE KEYHANI
Hypoxia/Anoxia as Signaling for Increased Alcohol Dehydrogenase Activity in Saffron (Crocus sativus L.) Corm
Ann NY Acad Sci 2004 1030: 449-457. [Abstract] [Full Text]  

A KYRIAKOPOULOS, K BUKALIS, D ROETHLEIN, B HOPPE, A GRAEBERT, and D BEHNE
Prevention Against Oxidative Stress of Eukaryotic Cell Membranes by Selenium Compounds of the Rat
Ann NY Acad Sci 2004 1030: 458-461. [Abstract] [Full Text]  

FAUSTO MORONI, RINA RECCHIONI, FIORELLA MARCHESELLI, PATRIZIA FATTORETTI, and CARLO BERTONI-FREDDARI
Effect of Dietary Restriction on DNA Synthesis in Vitamin E-Deficient Rats
Ann NY Acad Sci 2004 1030: 462-467. [Abstract] [Full Text]  

Part VI. Gene Expression Mechanisms as Therapeutic Targets:

MARGARIDA FARDILHA, WENJUAN WU, ROSÁLIA SÁ, SARA FIDALGO, CRISTINA SOUSA, CATARINA MOTA, ODETE A.B. DA CRUZ E SILVA, and EDGAR F. DA CRUZ E SILVA
Alternatively Spliced Protein Variants as Potential Therapeutic Targets for Male Infertility and Contraception
Ann NY Acad Sci 2004 1030: 468-478. [Abstract] [Full Text]  

OLAF BARTSCHA and RICHARD IVELL
Relaxin and Phosphodiesterases Collaborate during Decidualization
Ann NY Acad Sci 2004 1030: 479-492. [Abstract] [Full Text]  

EUN-HEE KIM, DO-HEE KIM, HYE-KYUNG NA, and YOUNG-JOON SURH
Effects of Cyclopentenone Prostaglandins on the Expression of Heme Oxygenase-1 in MCF-7 Cells
Ann NY Acad Sci 2004 1030: 493-500. [Abstract] [Full Text]  

KI WON LEE, KYUNG-SOO CHUN, JEONG-SANG LEE, KYUNG-SUN KANG, YOUNG-JOON SURH, and HYONG JOO LEE
Inhibition of Cyclooxygenase-2 Expression and Restoration of Gap Junction Intercellular Communication in H-ras-Transformed Rat Liver Epithelial Cells by Caffeic Acid Phenethyl Ester
Ann NY Acad Sci 2004 1030: 501-507. [Abstract] [Full Text]  

ABDOMINAL OBESITY STUDY GROUP, FINN EDLER VON EYBEN, JENS PETER KROUSTRUP, JENS FROMHOLT LARSEN, and JULIO CELIS
Comparison of Gene Expression in Intra-Abdominal and Subcutaneous Fat: A Study of Men with Morbid Obesity and Nonobese Men Using Microarray and Proteomics
Ann NY Acad Sci 2004 1030: 508-536. [Abstract] [Full Text]  

Part VII. Transcriptional Control Mechanisms as Therapeutic Targets:

FRANCK MORCEAU, MICHAEL SCHNEKENBURGER, MARIO DICATO, and MARC DIEDERICH
GATA-1: Friends, Brothers, and Coworkers
Ann NY Acad Sci 2004 1030: 537-554. [Abstract] [Full Text]  

HEE-GU LEE, HYOSON KIM, WON-KEUN OH, KYUNG-AE YU, YONG-KYUNG CHOE, JONG-SEOG AHN, DONG-SOO KIM, SOO-HYUN KIM, CHARLES A. DINARELLO, KILHYOUN KIM, and DO-YOUNG YOON
Tetramethoxy Hydroxyflavone p7F Downregulates Inflammatory Mediators via the Inhibition of Nuclear Factor {kappa}B
Ann NY Acad Sci 2004 1030: 555-568. [Abstract] [Full Text]  

JURATE SAVICKIENE, GRAZINA TREIGYTE, AUGUSTAS PIVORIUNAS, RUTA NAVAKAUSKIENE, and KARL-ERIC MAGNUSSON
Sp1 and NF-{kappa}B Transcription Factor Activity in the Regulation of the p21 and FasL Promoters during Promyelocytic Leukemia Cell Monocytic Differentiation and Its Associated Apoptosis
Ann NY Acad Sci 2004 1030: 569-577. [Abstract] [Full Text]  

GUNDULA SCHULZE-TANZIL, ALI MOBASHERI, JUDITH SENDZIK, THILO JOHN, and MEHDI SHAKIBAEI
Effects of Curcumin (Diferuloylmethane) on Nuclear Factor {kappa}B Signaling in Interleukin-1ß-Stimulated Chondrocytes
Ann NY Acad Sci 2004 1030: 578-586. [Abstract] [Full Text]  

TAMZIN TANNER, FRANK CLAESSENS, and ANNEMIE HAELENS
The Hinge Region of the Androgen Receptor Plays a Role in Proteasome-Mediated Transcriptional Activation
Ann NY Acad Sci 2004 1030: 587-592. [Abstract] [Full Text]  

Part VIII. Chromatin Structure as a Therapeutic Target:

MARIA A. PEREZ-LAMIGUEIRO and RAFAEL ALVAREZ-GONZALEZ
Polynucleosomal Synthesis of Poly(ADP-ribose) Causes Chromatin Unfolding as Determined by Micrococcal Nuclease Digestion
Ann NY Acad Sci 2004 1030: 593-598. [Abstract] [Full Text]  

BERNARD DAN, LAURENT SERVAIS, STEWART G. BOYD, JOSEPH WAGSTAFF, and GUY CHERON
From Electrophysiology to Chromatin: A Bottom-Up Approach to Angelman Syndrome
Ann NY Acad Sci 2004 1030: 599-611. [Abstract] [Full Text]  

NATHALIE DRUESNE, ANTHONY PAGNIEZ, CAMILLE MAYEUR, MURIEL THOMAS, CLAIRE CHERBUY, PIERRE-HENRI DUÉE, PAULE MARTEL, and CATHERINE CHAUMONTET
Repetitive Treatments of Colon HT-29 Cells with Diallyl Disulfide Induce a Prolonged Hyperacetylation of Histone H3 K14
Ann NY Acad Sci 2004 1030: 612-621. [Abstract] [Full Text]  

RIYO ENOMOTO, CHIYOKO SUGAHARA, YUKO TSUDA, YOSHIO OKADA, and EIBAI LEE
Thymocyte Apoptosis Induced by Various Compounds Including YO-2 Is Accompanied by a Change in Chromatin Structure
Ann NY Acad Sci 2004 1030: 622-626. [Abstract] [Full Text]  

BRIAN GABRIELLI, ROBYN WARRENER, ANDREW BURGESS, and HEATHER BEAMISH
Defining the Chemotherapeutic Targets of Histone Deacetylase Inhibitors
Ann NY Acad Sci 2004 1030: 627-635. [Abstract] [Full Text]  

GIULIA MARSILI, ANNA LISA REMOLI, MARCO SGARBANTI, and ANGELA BATTISTINI
Role of Acetylases and Deacetylase Inhibitors in IRF-1-Mediated HIV-1 Long Terminal Repeat Transcription
Ann NY Acad Sci 2004 1030: 636-643. [Abstract] [Full Text]  

JAMES M. NICHOLSON, CHRISTOPHER M. WOOD, COLIN D. REYNOLDS, ALAN BROWN, STANLEY J. LAMBERT, LAURENT CHANTALAT, and JOHN P. BALDWIN
Histone Structures: Targets for Modifications by Molecular Assemblies
Ann NY Acad Sci 2004 1030: 644-655. [Abstract] [Full Text]  

IRINA PANTELEEVA, CAROLINE ROUAUX, YVES LARMET, STÉPHANIE BOUTILLIER, JEAN-PHILIPPE LOEFFLER, and ANNE-LAURENCE BOUTILLIER
HDAC-3 Participates in the Repression of e2f-Dependent Gene Transcription in Primary Differentiated Neurons
Ann NY Acad Sci 2004 1030: 656-660. [Abstract] [Full Text]  

ZHONG ZHAO and WEN-HUI SHEN
Plants Contain a High Number of Proteins Showing Sequence Similarity to the Animal SUV39H Family of Histone Methyltransferases
Ann NY Acad Sci 2004 1030: 661-669. [Abstract] [Full Text]  

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